Research Associate
Dr. Linu Balan
- csb.linu@gmail.com
Centre for Synthetic Biology and Bio-Manufacturing, CUSAT
Dr Linu Balan is currently serving as a Research Associate at the Centre for Synthetic Biology and Bio-Manufacturing. Dr Balan’s academic foundation began with a B.Tech. in Biotechnology and Biochemical Engineering from Sree Buddha College of Engineering, Pattoor, in 2007, followed by a Laboratory Course in BioTechniques (PG Diploma) at the Institute of Bioinformatics and Applied Biotechnology, Bengaluru, in 2008. He went on to complete his M. Tech. in Marine Biotechnology at the National Centre for Aquatic Animal Health, CUSAT, in 2010, laying the groundwork for his subsequent research in marine microbial systems. He earned his PhD from CUSAT, with a thesis entitled “Polyhydroxyalkanoates from Marine Microorganisms for Aquaculture Applications.”
During his doctoral studies, he established a comprehensive repository of PHA-producing bacteria isolated from India’s west coast, screened and selected high-yield strains, optimised both production and downstream processing of polyhydroxybutyrate, and pioneered PHB nanoparticle formulations loaded with dsRNA as well as a bacterin to prevent vibriosis in Penaeus monodon post-larvae. He also founded a spinoff firm that focuses on PHA synthesis. His areas of expertise include microbial biotechnology, bioprocess technology, molecular biology, and nanomaterials.
Breif Research Statement
Dr Balan’s research focuses on the production of biopolymers, with particular emphasis on polyhydroxyalkanoates, which serve as eco-friendly alternatives to synthetic plastics. His current work involves developing microbial strains capable of producing these polymers more efficiently, achieving higher yields and enhanced material properties.
In addition, he is actively engaged in scaling up polymer production through bioreactor optimisation, ensuring that laboratory successes can be translated into industrial applications. Beyond production, Dr Balan also explores innovative biomedical applications, including the development of delivery systems using polymer-based nanoparticles, highlighting the versatility and impact of his research.
Publications
- Balan, L., Mohandas, S.P., Priyaja, P., Gopi, J., Cubelio, S.S., Philip, R., Bright Singh, I.S., 2025. Development of a mini-repository of marine bacteria having the potential of Polyhydroxyalkanoates production. The Microbe 7, 100338. https://doi.org/10.1016/j.microb.2025.100338
- Mohandas, S.P., Balan, L., Gopi, J., Anoop, B.S., Mohan P, S., Philip, R., Cubelio, S.S., Singh, I.S.B., 2021. Biocompatibility of polyhydroxybutyrate-co-hydroxyvalerate films generated from Bacillus cereus MCCB 281 for medical applications. Int. J. Biol. Macromol. 176, 244–252. doi:10.1016/j.ijbiomac.2021.02.006
- Mohandas, S.P., Balan, L., Jayanath, G., Anoop, B.S., Philip, R., Cubelio, S.S., Bright Singh, I.S., 2018. Biosynthesis and characterization of polyhydroxyalkanoate from marine Bacillus cereus MCCB 281 utilizing glycerol as carbon source. Int. J. Biol. Macromol. 119, 380–392. doi:10.1016/j.ijbiomac.2018.07.044
- Mohandas, S.P., Balan, L., Lekshmi, N., Cubelio, S.S., Philip, R., Bright Singh, I.S., 2017. Production and characterization of polyhydroxybutyrate from Vibrio harveyi MCCB 284 utilizing glycerol as carbon source. J. Appl. Microbiol. 122, 698–707. doi: 10.1111/jam.13359
achievements
- CSIR NET (LS) 2010, 2013
- Graduate Aptitude Test in Engineering (GATE) in Biotechnology (2010)
- Recipient of RUSA CUSATECH Idea Grant for the year 2020